Maria

Managing Chronic Conditions with Precision
55-year-old with newly diagnosed type 2 diabetes and a family history of cardiovascular disease, is struggling to control her blood sugar and reduce her cardiovascular risk.

Case 1: Maria - Managing Chronic Conditions with Precision

Level 1: Clinical Data Analysed

Data: HbA1c at 8.2%, LDL total cholesterol at 176 mg/dL, blood pressure at 143/91 mmHg.

Recommendation: Initiate metformin for diabetes, statin therapy for dyslipidemia, and lifestyle modifications for blood pressure control.

Expected Outcome: Improved glycemic control, lower LDL cholesterol levels, and normalised blood pressure.

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Level 2: Behavioural Data from Digital Markers

Data: Wearable data shows an average of 3,500 steps per day and 5 hours of sedentary activity.

Recommendation: Increase daily step goal to 7,000 and introduce 30 minutes of moderate exercise 5 days a week.

Expected Outcome: Enhanced physical fitness, weight loss, and better glycemic control.

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Level 3: Genetic Biomarkers and Microbiome Data

Genetic Data: Presence of a variant in the TCF7L2 gene, increasing her risk for Type 2 diabetes.

Recommendation: Dietary adjustments to include more fiber-rich foods to support gut health, alongside medication adjustments based on genetic risk.

Expected Outcome: Improved gut microbiome composition and more effective management of diabetes.

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Level 4: Data on Community and Environment

Data: Lives in an urban area with high levels of air pollution.

Recommendation: Use of air purifiers at home and minimise outdoor activities during peak pollution hours.

Expected Outcome: Reduced exposure to harmful pollutants, potentially lowering the risk of cardiovascular complications.

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